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Jan 5

Time Series Analysis for Education: Methods, Applications, and Future Directions

Recent advancements in the collection and analysis of sequential educational data have brought time series analysis to a pivotal position in educational research, highlighting its essential role in facilitating data-driven decision-making. However, there is a lack of comprehensive summaries that consolidate these advancements. To the best of our knowledge, this paper is the first to provide a comprehensive review of time series analysis techniques specifically within the educational context. We begin by exploring the landscape of educational data analytics, categorizing various data sources and types relevant to education. We then review four prominent time series methods-forecasting, classification, clustering, and anomaly detection-illustrating their specific application points in educational settings. Subsequently, we present a range of educational scenarios and applications, focusing on how these methods are employed to address diverse educational tasks, which highlights the practical integration of multiple time series methods to solve complex educational problems. Finally, we conclude with a discussion on future directions, including personalized learning analytics, multimodal data fusion, and the role of large language models (LLMs) in educational time series. The contributions of this paper include a detailed taxonomy of educational data, a synthesis of time series techniques with specific educational applications, and a forward-looking perspective on emerging trends and future research opportunities in educational analysis. The related papers and resources are available and regularly updated at the project page.

  • 7 authors
·
Aug 25, 2024

Building Flexible, Scalable, and Machine Learning-ready Multimodal Oncology Datasets

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is essential for developing a holistic understanding of the disease and optimizing treatment. The need for integrating data from multiple sources is further pronounced in complex diseases such as cancer for enabling precision medicine and personalized treatments. This work proposes Multimodal Integration of Oncology Data System (MINDS) - a flexible, scalable, and cost-effective metadata framework for efficiently fusing disparate data from public sources such as the Cancer Research Data Commons (CRDC) into an interconnected, patient-centric framework. MINDS offers an interface for exploring relationships across data types and building cohorts for developing large-scale multimodal machine learning models. By harmonizing multimodal data, MINDS aims to potentially empower researchers with greater analytical ability to uncover diagnostic and prognostic insights and enable evidence-based personalized care. MINDS tracks granular end-to-end data provenance, ensuring reproducibility and transparency. The cloud-native architecture of MINDS can handle exponential data growth in a secure, cost-optimized manner while ensuring substantial storage optimization, replication avoidance, and dynamic access capabilities. Auto-scaling, access controls, and other mechanisms guarantee pipelines' scalability and security. MINDS overcomes the limitations of existing biomedical data silos via an interoperable metadata-driven approach that represents a pivotal step toward the future of oncology data integration.

  • 5 authors
·
Sep 30, 2023

Multimodal Deep Learning of Word-of-Mouth Text and Demographics to Predict Customer Rating: Handling Consumer Heterogeneity in Marketing

In the marketing field, understanding consumer heterogeneity, which is the internal or psychological difference among consumers that cannot be captured by behavioral logs, has long been a critical challenge. However, a number of consumers today usually post their evaluation on the specific product on the online platform, which can be the valuable source of such unobservable differences among consumers. Several previous studies have shown the validity of the analysis on text modality, but on the other hand, such analyses may not necessarily demonstrate sufficient predictive accuracy for text alone, as they may not include information readily available from cross-sectional data, such as consumer profile data. In addition, recent advances in machine learning techniques, such as large-scale language models (LLMs) and multimodal learning have made it possible to deal with the various kind of dataset simultaneously, including textual data and the traditional cross-sectional data, and the joint representations can be effectively obtained from multiple modalities. Therefore, this study constructs a product evaluation model that takes into account consumer heterogeneity by multimodal learning of online product reviews and consumer profile information. We also compare multiple models using different modalities or hyper-parameters to demonstrate the robustness of multimodal learning in marketing analysis.

  • 1 authors
·
Jan 22, 2024

Improving Multimodal Learning via Imbalanced Learning

Multimodal learning often encounters the under-optimized problem and may perform worse than unimodal learning. Existing approaches attribute this issue to imbalanced learning across modalities and tend to address it through gradient balancing. However, this paper argues that balanced learning is not the optimal setting for multimodal learning. With bias-variance analysis, we prove that imbalanced dependency on each modality obeying the inverse ratio of their variances contributes to optimal performance. To this end, we propose the Asymmetric Representation Learning(ARL) strategy to assist multimodal learning via imbalanced optimization. ARL introduces auxiliary regularizers for each modality encoder to calculate their prediction variance. ARL then calculates coefficients via the unimodal variance to re-weight the optimization of each modality, forcing the modality dependence ratio to be inversely proportional to the modality variance ratio. Moreover, to minimize the generalization error, ARL further introduces the prediction bias of each modality and jointly optimizes them with multimodal loss. Notably, all auxiliary regularizers share parameters with the multimodal model and rely only on the modality representation. Thus the proposed ARL strategy introduces no extra parameters and is independent of the structures and fusion methods of the multimodal model. Finally, extensive experiments on various datasets validate the effectiveness and versatility of ARL. Code is available at https://github.com/shicaiwei123/ICCV2025-ARL{https://github.com/shicaiwei123/ICCV2025-ARL}

  • 3 authors
·
Jul 14, 2025

An Efficient Multimodal Learning Framework to Comprehend Consumer Preferences Using BERT and Cross-Attention

Today, the acquisition of various behavioral log data has enabled deeper understanding of customer preferences and future behaviors in the marketing field. In particular, multimodal deep learning has achieved highly accurate predictions by combining multiple types of data. Many of these studies utilize with feature fusion to construct multimodal models, which combines extracted representations from each modality. However, since feature fusion treats information from each modality equally, it is difficult to perform flexible analysis such as the attention mechanism that has been used extensively in recent years. Therefore, this study proposes a context-aware multimodal deep learning model that combines Bidirectional Encoder Representations from Transformers (BERT) and cross-attention Transformer, which dynamically changes the attention of deep-contextualized word representations based on background information such as consumer demographic and lifestyle variables. We conduct a comprehensive analysis and demonstrate the effectiveness of our model by comparing it with six reference models in three categories using behavioral logs stored on an online platform. In addition, we present an efficient multimodal learning method by comparing the learning efficiency depending on the optimizers and the prediction accuracy depending on the number of tokens in the text data.

  • 1 authors
·
May 12, 2024

WavCaps: A ChatGPT-Assisted Weakly-Labelled Audio Captioning Dataset for Audio-Language Multimodal Research

The advancement of audio-language (AL) multimodal learning tasks has been significant in recent years. However, researchers face challenges due to the costly and time-consuming collection process of existing audio-language datasets, which are limited in size. To address this data scarcity issue, we introduce WavCaps, the first large-scale weakly-labelled audio captioning dataset, comprising approximately 400k audio clips with paired captions. We sourced audio clips and their raw descriptions from web sources and a sound event detection dataset. However, the online-harvested raw descriptions are highly noisy and unsuitable for direct use in tasks such as automated audio captioning. To overcome this issue, we propose a three-stage processing pipeline for filtering noisy data and generating high-quality captions, where ChatGPT, a large language model, is leveraged to filter and transform raw descriptions automatically. We conduct a comprehensive analysis of the characteristics of WavCaps dataset and evaluate it on multiple downstream audio-language multimodal learning tasks. The systems trained on WavCaps outperform previous state-of-the-art (SOTA) models by a significant margin. Our aspiration is for the WavCaps dataset we have proposed to facilitate research in audio-language multimodal learning and demonstrate the potential of utilizing ChatGPT to enhance academic research. Our dataset and codes are available at https://github.com/XinhaoMei/WavCaps.

  • 9 authors
·
Mar 30, 2023

A Survey on (M)LLM-Based GUI Agents

Graphical User Interface (GUI) Agents have emerged as a transformative paradigm in human-computer interaction, evolving from rule-based automation scripts to sophisticated AI-driven systems capable of understanding and executing complex interface operations. This survey provides a comprehensive examination of the rapidly advancing field of LLM-based GUI Agents, systematically analyzing their architectural foundations, technical components, and evaluation methodologies. We identify and analyze four fundamental components that constitute modern GUI Agents: (1) perception systems that integrate text-based parsing with multimodal understanding for comprehensive interface comprehension; (2) exploration mechanisms that construct and maintain knowledge bases through internal modeling, historical experience, and external information retrieval; (3) planning frameworks that leverage advanced reasoning methodologies for task decomposition and execution; and (4) interaction systems that manage action generation with robust safety controls. Through rigorous analysis of these components, we reveal how recent advances in large language models and multimodal learning have revolutionized GUI automation across desktop, mobile, and web platforms. We critically examine current evaluation frameworks, highlighting methodological limitations in existing benchmarks while proposing directions for standardization. This survey also identifies key technical challenges, including accurate element localization, effective knowledge retrieval, long-horizon planning, and safety-aware execution control, while outlining promising research directions for enhancing GUI Agents' capabilities. Our systematic review provides researchers and practitioners with a thorough understanding of the field's current state and offers insights into future developments in intelligent interface automation.

  • 15 authors
·
Mar 27, 2025

Spotlight on Token Perception for Multimodal Reinforcement Learning

While Reinforcement Learning with Verifiable Rewards (RLVR) has advanced the reasoning capabilities of Large Vision-Language Models (LVLMs), most existing methods in multimodal reasoning neglect the critical role of visual perception within the RLVR optimization process. In this paper, we undertake a pioneering exploration of multimodal RLVR through the novel perspective of token perception, which measures the visual dependency of each generated token. With a granular analysis of Chain-of-Thought (CoT) processes, we uncover two key insights: first, token perception in a rollout trajectory is sparsely distributed, where only a small fraction of tokens have high visual dependency for visually-grounded reasoning; second, different trajectories exhibit significant divergence in their overall visual dependency. Based on these observations, we propose Visually-Perceptive Policy Optimization (VPPO), a novel policy gradient algorithm that explicitly leverages token perception to refine the learning signal. Specifically, VPPO achieves this through a dual mechanism: it reweights a trajectory's advantage by its overall visual dependency, and focuses policy updates exclusively on perceptually pivotal tokens. On a comprehensive suite of eight perception and reasoning benchmarks, VPPO demonstrates substantial gains over leading open-source RL-tuned models, with its effectiveness consistently validated across 7B and 32B model scales. Our findings not only establish a new token-level perceptual perspective for analyzing multimodal RLVR but also present a novel and effective optimization strategy to significantly enhance the multimodal reasoning capabilities of LVLMs.

  • 7 authors
·
Oct 10, 2025 3

DLF: Disentangled-Language-Focused Multimodal Sentiment Analysis

Multimodal Sentiment Analysis (MSA) leverages heterogeneous modalities, such as language, vision, and audio, to enhance the understanding of human sentiment. While existing models often focus on extracting shared information across modalities or directly fusing heterogeneous modalities, such approaches can introduce redundancy and conflicts due to equal treatment of all modalities and the mutual transfer of information between modality pairs. To address these issues, we propose a Disentangled-Language-Focused (DLF) multimodal representation learning framework, which incorporates a feature disentanglement module to separate modality-shared and modality-specific information. To further reduce redundancy and enhance language-targeted features, four geometric measures are introduced to refine the disentanglement process. A Language-Focused Attractor (LFA) is further developed to strengthen language representation by leveraging complementary modality-specific information through a language-guided cross-attention mechanism. The framework also employs hierarchical predictions to improve overall accuracy. Extensive experiments on two popular MSA datasets, CMU-MOSI and CMU-MOSEI, demonstrate the significant performance gains achieved by the proposed DLF framework. Comprehensive ablation studies further validate the effectiveness of the feature disentanglement module, language-focused attractor, and hierarchical predictions. Our code is available at https://github.com/pwang322/DLF.

  • 5 authors
·
Dec 16, 2024

InverTune: Removing Backdoors from Multimodal Contrastive Learning Models via Trigger Inversion and Activation Tuning

Multimodal contrastive learning models like CLIP have demonstrated remarkable vision-language alignment capabilities, yet their vulnerability to backdoor attacks poses critical security risks. Attackers can implant latent triggers that persist through downstream tasks, enabling malicious control of model behavior upon trigger presentation. Despite great success in recent defense mechanisms, they remain impractical due to strong assumptions about attacker knowledge or excessive clean data requirements. In this paper, we introduce InverTune, the first backdoor defense framework for multimodal models under minimal attacker assumptions, requiring neither prior knowledge of attack targets nor access to the poisoned dataset. Unlike existing defense methods that rely on the same dataset used in the poisoning stage, InverTune effectively identifies and removes backdoor artifacts through three key components, achieving robust protection against backdoor attacks. Specifically, InverTune first exposes attack signatures through adversarial simulation, probabilistically identifying the target label by analyzing model response patterns. Building on this, we develop a gradient inversion technique to reconstruct latent triggers through activation pattern analysis. Finally, a clustering-guided fine-tuning strategy is employed to erase the backdoor function with only a small amount of arbitrary clean data, while preserving the original model capabilities. Experimental results show that InverTune reduces the average attack success rate (ASR) by 97.87% against the state-of-the-art (SOTA) attacks while limiting clean accuracy (CA) degradation to just 3.07%. This work establishes a new paradigm for securing multimodal systems, advancing security in foundation model deployment without compromising performance.

  • 5 authors
·
Jun 14, 2025

MLLM-CBench:A Comprehensive Benchmark for Continual Instruction Tuning of Multimodal LLMs with Chain-of-Thought Reasoning Analysis

Multimodal large language models (MLLMs) require continual instruction tuning during their post-training phase to adapt to the dynamic real-world demands. However, the absence of rigorous and systematic benchmarks has hindered progress in this area. To bridge this gap, we introduce MLLM-CTBench, a dataset curating seven challenging tasks from six diverse domains with three contributions. First,to enable fine-grained analysis of continual learning ability, we introduce multidimensional evaluation metrics, which combines final answer accuracy with Chain-of-Thought (CoT) reasoning quality assessment through a carefully trained MLLM evaluator. Then, we conduct a comprehensive evaluation of continual learning algorithms, systematically assessing eight algorithms from four major categories to provide actionable insights for algorithm design and adoption. Finally ,we evaluate the efficacy of Reinforcement Fine-tuning (RFT) versus Supervised Fine-tuning (SFT) in maintaining model performance across sequential tasks during continual instruction tuning. Our experiments demonstrate that reasoning processes in MLLMs exhibit greater resilience than final outputs to forgetting during continual learning, aligning with cognitive theories of hierarchical forgetting. We further show that both model capability and task sequence significantly influence continual learning outcomes, with stronger baseline models exhibiting greater resistance to forgetting. Notably, properly regularized RFT emerges as a more robust approach than SFT for maintaining performance across tasks.One of the key contributing factors is KL-divergence regularization, without which RFT leads to even worse forgetting than SFT on old tasks though may perform better on new tasks.

  • 9 authors
·
Jul 31, 2025

Memory-Augmented Incomplete Multimodal Survival Prediction via Cross-Slide and Gene-Attentive Hypergraph Learning

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of other preservation slides, such as Fresh Froze (FF) slides. Moreover, as the high-resolution spatial nature of pathology data tends to dominate the cross-modality fusion process, it hinders effective multimodal fusion and leads to modality imbalance challenges between pathology and genomics. These methods also typically require complete data modalities, limiting their clinical applicability with incomplete modalities, such as missing either pathology or genomic data. In this paper, we propose a multimodal survival prediction framework that leverages hypergraph learning to effectively integrate multi-WSI information and cross-modality interactions between pathology slides and genomics data while addressing modality imbalance. In addition, we introduce a memory mechanism that stores previously learned paired pathology-genomic features and dynamically compensates for incomplete modalities. Experiments on five TCGA datasets demonstrate that our model outperforms advanced methods by over 2.3% in C-Index. Under incomplete modality scenarios, our approach surpasses pathology-only (3.3%) and gene-only models (7.9%). Code: https://github.com/MCPathology/M2Surv

  • 7 authors
·
Jun 24, 2025

AgroSense: An Integrated Deep Learning System for Crop Recommendation via Soil Image Analysis and Nutrient Profiling

Meeting the increasing global demand for food security and sustainable farming requires intelligent crop recommendation systems that operate in real time. Traditional soil analysis techniques are often slow, labor-intensive, and not suitable for on-field decision-making. To address these limitations, we introduce AgroSense, a deep-learning framework that integrates soil image classification and nutrient profiling to produce accurate and contextually relevant crop recommendations. AgroSense comprises two main components: a Soil Classification Module, which leverages ResNet-18, EfficientNet-B0, and Vision Transformer architectures to categorize soil types from images; and a Crop Recommendation Module, which employs a Multi-Layer Perceptron, XGBoost, LightGBM, and TabNet to analyze structured soil data, including nutrient levels, pH, and rainfall. We curated a multimodal dataset of 10,000 paired samples drawn from publicly available Kaggle repositories, approximately 50,000 soil images across seven classes, and 25,000 nutrient profiles for experimental evaluation. The fused model achieves 98.0% accuracy, with a precision of 97.8%, a recall of 97.7%, and an F1-score of 96.75%, while RMSE and MAE drop to 0.32 and 0.27, respectively. Ablation studies underscore the critical role of multimodal coupling, and statistical validation via t-tests and ANOVA confirms the significance of our improvements. AgroSense offers a practical, scalable solution for real-time decision support in precision agriculture and paves the way for future lightweight multimodal AI systems in resource-constrained environments.

  • 3 authors
·
Sep 1, 2025

Zero-Shot Multi-Spectral Learning: Reimagining a Generalist Multimodal Gemini 2.5 Model for Remote Sensing Applications

Multi-spectral imagery plays a crucial role in diverse Remote Sensing applications including land-use classification, environmental monitoring and urban planning. These images are widely adopted because their additional spectral bands correlate strongly with physical materials on the ground, such as ice, water, and vegetation. This allows for more accurate identification, and their public availability from missions, such as Sentinel-2 and Landsat, only adds to their value. Currently, the automatic analysis of such data is predominantly managed through machine learning models specifically trained for multi-spectral input, which are costly to train and support. Furthermore, although providing a lot of utility for Remote Sensing, such additional inputs cannot be used with powerful generalist large multimodal models, which are capable of solving many visual problems, but are not able to understand specialized multi-spectral signals. To address this, we propose a training-free approach which introduces new multi-spectral data in a Zero-Shot-only mode, as inputs to generalist multimodal models, trained on RGB-only inputs. Our approach leverages the multimodal models' understanding of the visual space, and proposes to adapt to inputs to that space, and to inject domain-specific information as instructions into the model. We exemplify this idea with the Gemini2.5 model and observe strong Zero-Shot performance gains of the approach on popular Remote Sensing benchmarks for land cover and land use classification and demonstrate the easy adaptability of Gemini2.5 to new inputs. These results highlight the potential for geospatial professionals, working with non-standard specialized inputs, to easily leverage powerful multimodal models, such as Gemini2.5, to accelerate their work, benefiting from their rich reasoning and contextual capabilities, grounded in the specialized sensor data.

  • 7 authors
·
Sep 23, 2025 2

MM-R5: MultiModal Reasoning-Enhanced ReRanker via Reinforcement Learning for Document Retrieval

Multimodal document retrieval systems enable information access across text, images, and layouts, benefiting various domains like document-based question answering, report analysis, and interactive content summarization. Rerankers improve retrieval precision by reordering retrieved candidates. However, current multimodal reranking methods remain underexplored, with significant room for improvement in both training strategies and overall effectiveness. Moreover, the lack of explicit reasoning makes it difficult to analyze and optimize these methods further. In this paper, We propose MM-R5, a MultiModal Reasoning-Enhanced ReRanker via Reinforcement Learning for Document Retrieval, aiming to provide a more effective and reliable solution for multimodal reranking tasks. MM-R5 is trained in two stages: supervised fine-tuning (SFT) and reinforcement learning (RL). In the SFT stage, we focus on improving instruction-following and guiding the model to generate complete and high-quality reasoning chains. To support this, we introduce a novel data construction strategy that produces rich, high-quality reasoning data. In the RL stage, we design a task-specific reward framework, including a reranking reward tailored for multimodal candidates and a composite template-based reward to further refine reasoning quality. We conduct extensive experiments on MMDocIR, a challenging public benchmark spanning multiple domains. MM-R5 achieves state-of-the-art performance on most metrics and delivers comparable results to much larger models on the remaining ones. Moreover, compared to the best retrieval-only method, MM-R5 improves recall@1 by over 4%. These results validate the effectiveness of our reasoning-enhanced training pipeline.

  • 8 authors
·
Jun 14, 2025

VSLLaVA: a pipeline of large multimodal foundation model for industrial vibration signal analysis

While Large Multimodal Models (LMMs) excel in general multimodal tasks, they lack the domain-specific knowledge for industrial vibration signal analysis. This paper introduces VSLLaVA, a comprehensive pipeline that utilizes expert knowledge-guided instruction tuning and evaluation to create an end-to-end LMM for signal analysis. To achieve this, we construct a novel Signal-Question-Answer (SQA) dataset using an expert rule-based signal generator. This dataset facilitates a two-stage learning procedure. The first step is efficient instruction fine-tuning with Low-Rank Adaptation (LoRA), which imparts specialized signal identification capabilities. Subsequently, we designed a tailored Group Relative Policy Optimization (GRPO) to refine the reasoning capabilities and enhance classification robustness. Then, a dual-mode evaluation framework is proposed, combining an LLM referee with expert rules for semantic assessment using quantitative metrics for numerical and textual accuracy, which reveals that VSLLaVA significantly improves performance in signal type identification and parameter analysis, and makes progress in the identification and parameter analysis of fault-related signals. This research demonstrates a viable approach for developing specialized foundational models for complex industrial applications and marks a transition from conventional task-specific systems to a cohesive, interactive foundational model.

  • 7 authors
·
Sep 3, 2024

Harvard Glaucoma Detection and Progression: A Multimodal Multitask Dataset and Generalization-Reinforced Semi-Supervised Learning

Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal imaging data of optical coherence tomography (OCT). To address the data scarcity issue, this paper proposes two solutions. First, we develop a novel generalization-reinforced semi-supervised learning (SSL) model called pseudo supervisor to optimally utilize unlabeled data. Compared with SOTA models, the proposed pseudo supervisor optimizes the policy of predicting pseudo labels with unlabeled samples to improve empirical generalization. Our pseudo supervisor model is evaluated with two clinical tasks consisting of glaucoma detection and progression forecasting. The progression forecasting task is evaluated both unimodally and multimodally. Our pseudo supervisor model demonstrates superior performance than SOTA SSL comparison models. Moreover, our model also achieves the best results on the publicly available LAG fundus dataset. Second, we introduce the Harvard Glaucoma Detection and Progression (Harvard-GDP) Dataset, a multimodal multitask dataset that includes data from 1,000 patients with OCT imaging data, as well as labels for glaucoma detection and progression. This is the largest glaucoma detection dataset with 3D OCT imaging data and the first glaucoma progression forecasting dataset that is publicly available. Detailed sex and racial analysis are provided, which can be used by interested researchers for fairness learning studies. Our released dataset is benchmarked with several SOTA supervised CNN and transformer deep learning models. The dataset and code are made publicly available via https://ophai.hms.harvard.edu/datasets/harvard-gdp1000.

  • 5 authors
·
Aug 25, 2023

Unimedvl: Unifying Medical Multimodal Understanding And Generation Through Observation-Knowledge-Analysis

Medical diagnostic applications require models that can process multimodal medical inputs (images, patient histories, lab results) and generate diverse outputs including both textual reports and visual content (annotations, segmentation masks, and images). Despite this need, existing medical AI systems disrupt this unified process: medical image understanding models interpret images but cannot generate visual outputs, while medical image generation models synthesize images but cannot provide textual explanations. This leads to gaps in data representation, feature integration, and task-level multimodal capabilities. To this end, we propose a multi-level framework that draws inspiration from diagnostic workflows through the Observation-Knowledge-Analysis (OKA) paradigm. Specifically, at the observation level, we construct UniMed-5M, a dataset comprising over 5.6M samples that reformat diverse unimodal data into multimodal pairs for foundational observation. At the knowledge level, we propose Progressive Curriculum Learning that systematically introduces medical multimodal knowledge. At the analysis level, we introduce UniMedVL, the first medical unified multimodal model for the simultaneous analysis of image understanding and generation tasks within a single architecture. UniMedVL achieves superior performance on five medical image understanding benchmarks, while matching specialized models in generation quality across eight medical imaging modalities. Crucially, our unified architecture enables bidirectional knowledge sharing: generation tasks enhance visual understanding features, demonstrating that integrating traditionally separate capabilities within a single medical framework unlocks improvements across diverse medical vision-language tasks. Code is available at https://github.com/uni-medical/UniMedVL.

General-Medical-AI General Medical AI
·
Oct 17, 2025 3

Leveraging Generic Foundation Models for Multimodal Surgical Data Analysis

We investigate how both the adaptation of a generic foundation model via transfer learning and the integration of complementary modalities from the operating room (OR) can support surgical data science. To this end, we use V-JEPA as the single-modality foundation of a multimodal model for minimally invasive surgery support. We analyze how the model's downstream performance can benefit (a) from finetuning on unlabeled surgical video data and (b) from providing additional time-resolved data streams from the OR in a multimodal setup. In an in-house dataset of liver surgery videos, we analyze the tasks of predicting hospital length of stay and postoperative complications. In videos of the public HeiCo dataset, we analyze the task of surgical phase recognition. As a baseline, we apply pretrained V-JEPA to all tasks. We then finetune it on unlabeled, held-out videos to investigate its change in performance after domain adaptation. Following the idea of modular decision support networks, we integrate additional data streams from the OR by training a separate encoder to form a shared representation space with V-JEPA's embeddings. Our experiments show that finetuning on domain-specific data increases model performance. On the in-house data, integrating additional time-resolved data likewise benefits the model. On the HeiCo data, accuracy of the pretrained video-only, single-modality baseline setup is on par with the top-performing submissions of the EndoVis2017 challenge, while finetuning on domain-specific data increases accuracy further. Our results thus demonstrate how surgical data science can leverage public, generic foundation models. Likewise, they indicate the potential of domain adaptation and of integrating suitable complementary data streams from the OR. To support further research, we release our code and model weights at https://github.com/DigitalSurgeryLab-Basel/ML-CDS-2025.

  • 5 authors
·
Sep 8, 2025

BioFusionNet: Deep Learning-Based Survival Risk Stratification in ER+ Breast Cancer Through Multifeature and Multimodal Data Fusion

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present BioFusionNet, a deep learning framework that fuses image-derived features with genetic and clinical data to achieve a holistic patient profile and perform survival risk stratification of ER+ breast cancer patients. We employ multiple self-supervised feature extractors, namely DINO and MoCoV3, pretrained on histopathology patches to capture detailed histopathological image features. We then utilise a variational autoencoder (VAE) to fuse these features, and harness the latent space of the VAE to feed into a self-attention network, generating patient-level features. Next, we develop a co-dual-cross-attention mechanism to combine the histopathological features with genetic data, enabling the model to capture the interplay between them. Additionally, clinical data is incorporated using a feed-forward network (FFN), further enhancing predictive performance and achieving comprehensive multimodal feature integration. Furthermore, we introduce a weighted Cox loss function, specifically designed to handle imbalanced survival data, which is a common challenge in the field. The proposed model achieves a mean concordance index (C-index) of 0.77 and a time-dependent area under the curve (AUC) of 0.84, outperforming state-of-the-art methods. It predicts risk (high versus low) with prognostic significance for overall survival (OS) in univariate analysis (HR=2.99, 95% CI: 1.88--4.78, p<0.005), and maintains independent significance in multivariate analysis incorporating standard clinicopathological variables (HR=2.91, 95% CI: 1.80--4.68, p<0.005). The proposed method not only improves model performance but also addresses a critical gap in handling imbalanced data.

  • 4 authors
·
Feb 16, 2024

Supervised Fine-Tuning or Contrastive Learning? Towards Better Multimodal LLM Reranking

In information retrieval, training reranking models mainly focuses on two types of objectives: metric learning (e.g. contrastive loss to increase the predicted scores on relevant query-document pairs) and classification (binary label prediction of relevance vs. irrelevance). For BERT-style encoders, various studies have shown that contrastive learning (CL) can be more effective than discriminative (classification) learning. However, for large language models (LLMs), classification via supervised fine-tuning (SFT), which predicts ''yes'' (resp. ''no'') token for relevant (resp. irrelevant) pairs, appears more promising as it aligns well with the generative nature of LLMs. This divergence raises a central question: which objective is intrinsically better suited to LLM-based reranking, and what mechanism underlies the difference? In this work, we conduct a comprehensive comparison and analysis between CL and SFT for reranking, taking the universal multimodal retrieval (UMR) as the experimental playground. We first decompose the objectives into two components: weight, which controls the magnitude of those updates, and direction, which guides the model updates, then present a unified framework for understanding their interactions. Through probing experiments, we find that SFT provides a substantially stronger weighting scheme than CL, whereas the preferred scoring direction shows no clear winner. Taken together, these results point to a consistent advantage of SFT over CL for LLM reranking. To further validate our findings, we conduct large-scale training with SFT and present new state-of-the-art rerankers on the MRB benchmark. We also provide ablations on SFT settings and expect our findings to benefit future research and applications in this area.

  • 9 authors
·
Oct 16, 2025

DocThinker: Explainable Multimodal Large Language Models with Rule-based Reinforcement Learning for Document Understanding

Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities in document understanding. However, their reasoning processes remain largely black-box, making it difficult to ensure reliability and trustworthiness, especially in high-stakes domains such as legal, financial, and medical document analysis. Existing methods use fixed Chain-of-Thought (CoT) reasoning with supervised fine-tuning (SFT) but suffer from catastrophic forgetting, poor adaptability, and limited generalization across domain tasks. In this paper, we propose DocThinker, a rule-based Reinforcement Learning (RL) framework for dynamic inference-time reasoning. Instead of relying on static CoT templates, DocThinker autonomously refines reasoning strategies via policy learning, generating explainable intermediate results, including structured reasoning processes, rephrased questions, regions of interest (RoI) supporting the answer, and the final answer. By integrating multi-objective rule-based rewards and KL-constrained optimization, our method mitigates catastrophic forgetting and enhances both adaptability and transparency. Extensive experiments on multiple benchmarks demonstrate that DocThinker significantly improves generalization while producing more explainable and human-understandable reasoning steps. Our findings highlight RL as a powerful alternative for enhancing explainability and adaptability in MLLM-based document understanding. Code will be available at https://github.com/wenwenyu/DocThinker.

  • 4 authors
·
Aug 11, 2025

VideoRewardBench: Comprehensive Evaluation of Multimodal Reward Models for Video Understanding

Multimodal reward models (MRMs) play a crucial role in the training, inference, and evaluation of Large Vision Language Models (LVLMs) by assessing response quality. However, existing benchmarks for evaluating MRMs in the video domain suffer from a limited number and diversity of questions, a lack of comprehensive evaluation dimensions, and inadequate evaluation of diverse types of MRMs. To address these gaps, we introduce VideoRewardBench, the first comprehensive benchmark covering four core aspects of video understanding: perception, knowledge, reasoning, and safety. Through our AI-assisted data pipeline, we curate a high-quality preference dataset of 1,563 annotated samples, including 1,482 unique videos and 1,559 distinct questions--15 times the number found in the most question-rich prior benchmark. Each sample is a triplet consisting of a video-text prompt, a chosen response, and a rejected response. We also conduct a comprehensive evaluation across 28 multimodal reward models spanning three categories: generative, discriminative, and semi-scalar. Results show that even the top-performing model GPT-4o achieves only 57.0% overall accuracy, and the state-of-the-art open-source model Qwen2.5-VL-72B reaches merely 53.3%. Our analysis further reveals three key insights: (i) MRMs trained with reinforcement learning (RL) do not necessarily exhibit stronger cross-modal generalization than those trained without RL; (ii) except for discriminative MRMs, other types of MRMs across varying model capacities can benefit from inference-time scaling; and (iii) variations in input video frame count have different effects on different types of MRMs. We believe VideoRewardBench offers a challenging and valuable benchmark for advancing the evaluation and development of MRMs in the video domain.

  • 7 authors
·
Aug 30, 2025

MM-PRM: Enhancing Multimodal Mathematical Reasoning with Scalable Step-Level Supervision

While Multimodal Large Language Models (MLLMs) have achieved impressive progress in vision-language understanding, they still struggle with complex multi-step reasoning, often producing logically inconsistent or partially correct solutions. A key limitation lies in the lack of fine-grained supervision over intermediate reasoning steps. To address this, we propose MM-PRM, a process reward model trained within a fully automated, scalable framework. We first build MM-Policy, a strong multimodal model trained on diverse mathematical reasoning data. Then, we construct MM-K12, a curated dataset of 10,000 multimodal math problems with verifiable answers, which serves as seed data. Leveraging a Monte Carlo Tree Search (MCTS)-based pipeline, we generate over 700k step-level annotations without human labeling. The resulting PRM is used to score candidate reasoning paths in the Best-of-N inference setup and achieves significant improvements across both in-domain (MM-K12 test set) and out-of-domain (OlympiadBench, MathVista, etc.) benchmarks. Further analysis confirms the effectiveness of soft labels, smaller learning rates, and path diversity in optimizing PRM performance. MM-PRM demonstrates that process supervision is a powerful tool for enhancing the logical robustness of multimodal reasoning systems. We release all our codes and data at https://github.com/ModalMinds/MM-PRM.

  • 7 authors
·
May 19, 2025 2

iReason: Multimodal Commonsense Reasoning using Videos and Natural Language with Interpretability

Causality knowledge is vital to building robust AI systems. Deep learning models often perform poorly on tasks that require causal reasoning, which is often derived using some form of commonsense knowledge not immediately available in the input but implicitly inferred by humans. Prior work has unraveled spurious observational biases that models fall prey to in the absence of causality. While language representation models preserve contextual knowledge within learned embeddings, they do not factor in causal relationships during training. By blending causal relationships with the input features to an existing model that performs visual cognition tasks (such as scene understanding, video captioning, video question-answering, etc.), better performance can be achieved owing to the insight causal relationships bring about. Recently, several models have been proposed that have tackled the task of mining causal data from either the visual or textual modality. However, there does not exist widespread research that mines causal relationships by juxtaposing the visual and language modalities. While images offer a rich and easy-to-process resource for us to mine causality knowledge from, videos are denser and consist of naturally time-ordered events. Also, textual information offers details that could be implicit in videos. We propose iReason, a framework that infers visual-semantic commonsense knowledge using both videos and natural language captions. Furthermore, iReason's architecture integrates a causal rationalization module to aid the process of interpretability, error analysis and bias detection. We demonstrate the effectiveness of iReason using a two-pronged comparative analysis with language representation learning models (BERT, GPT-2) as well as current state-of-the-art multimodal causality models.

  • 2 authors
·
Jun 24, 2021

Unified Reward Model for Multimodal Understanding and Generation

Recent advances in human preference alignment have significantly enhanced multimodal generation and understanding. A key approach is training reward models to guide preference optimization. However, existing models are often task-specific, limiting their adaptability across diverse visual applications. We also argue that jointly learning to assess multiple tasks may foster a synergistic effect, where improved image understanding enhances image generation assessment, and refined image evaluation benefits video assessment through better frame analysis. To this end, this paper proposes UnifiedReward, the first unified reward model for multimodal understanding and generation assessment, enabling both pairwise ranking and pointwise scoring, which can be employed for vision model preference alignment. Specifically, (1) we first develop UnifiedReward on our constructed large-scale human preference dataset, including both image and video generation/understanding tasks. (2) Then, it is utilized to automatically construct high-quality preference pair data based on the vision models, fine-gradually filtering their outputs through pair ranking and point sifting. (3) Finally, these data are used for their preference alignment through Direct Preference Optimization (DPO). Experimental results demonstrate that joint learning to assess diverse visual tasks can lead to substantial mutual benefits and we apply our pipeline to both image and video understanding/generation tasks, significantly improving the performance in each domain.

  • 5 authors
·
Mar 7, 2025 3

LEGION: Learning to Ground and Explain for Synthetic Image Detection

The rapid advancements in generative technology have emerged as a double-edged sword. While offering powerful tools that enhance convenience, they also pose significant social concerns. As defenders, current synthetic image detection methods often lack artifact-level textual interpretability and are overly focused on image manipulation detection, and current datasets usually suffer from outdated generators and a lack of fine-grained annotations. In this paper, we introduce SynthScars, a high-quality and diverse dataset consisting of 12,236 fully synthetic images with human-expert annotations. It features 4 distinct image content types, 3 categories of artifacts, and fine-grained annotations covering pixel-level segmentation, detailed textual explanations, and artifact category labels. Furthermore, we propose LEGION (LEarning to Ground and explain for Synthetic Image detectiON), a multimodal large language model (MLLM)-based image forgery analysis framework that integrates artifact detection, segmentation, and explanation. Building upon this capability, we further explore LEGION as a controller, integrating it into image refinement pipelines to guide the generation of higher-quality and more realistic images. Extensive experiments show that LEGION outperforms existing methods across multiple benchmarks, particularly surpassing the second-best traditional expert on SynthScars by 3.31% in mIoU and 7.75% in F1 score. Moreover, the refined images generated under its guidance exhibit stronger alignment with human preferences. The code, model, and dataset will be released.

  • 11 authors
·
Mar 19, 2025 2

Seeing is Believing? Mitigating OCR Hallucinations in Multimodal Large Language Models

Recent advancements in multimodal large language models have enhanced document understanding by integrating textual and visual information. However, existing models exhibit incompleteness within their paradigm in real-world scenarios, particularly under visual degradation. In such conditions, the current response paradigm often fails to adequately perceive visual degradation and ambiguity, leading to overreliance on linguistic priors or misaligned visual-textual reasoning. This difficulty in recognizing uncertainty frequently results in the generation of hallucinatory content, especially when a precise answer is not feasible. To better demonstrate and analyze this phenomenon and problem, we propose KIE-HVQA, the first benchmark dedicated to evaluating OCR hallucination in degraded document understanding. This dataset includes test samples spanning identity cards and invoices, with simulated real-world degradations for OCR reliability. This setup allows for evaluating models' capacity, under degraded input, to distinguish reliable visual information and answer accordingly, thereby highlighting the challenge of avoiding hallucination on uncertain data. To achieve vision-faithful reasoning and thereby avoid the aforementioned issues, we further introduce a GRPO-based framework featuring a novel reward mechanism. By incorporating a self-awareness of visual uncertainty and an analysis method that initiates refusal to answer to increase task difficulty within our supervised fine-tuning and reinforcement learning framework, we successfully mitigated hallucinations in ambiguous regions. Experiments on Qwen2.5-VL demonstrate that our 7B-parameter model achieves a 22\% absolute improvement in hallucination-free accuracy over GPT-4o on KIE-HVQA and there is no significant performance drop in standard tasks, highlighting both effectiveness and robustness.

  • 9 authors
·
Jun 25, 2025

LLM-Guided Probabilistic Fusion for Label-Efficient Document Layout Analysis

Document layout understanding remains data-intensive despite advances in semi-supervised learning. We present a framework that enhances semi-supervised detection by fusing visual predictions with structural priors from text-pretrained LLMs via principled probabilistic weighting. Given unlabeled documents, an OCR-LLM pipeline infers hierarchical regions which are combined with teacher detector outputs through inverse-variance fusion to generate refined pseudo-labels.Our method demonstrates consistent gains across model scales. With a lightweight SwiftFormer backbone (26M params), we achieve 88.2pm0.3 AP using only 5\% labels on PubLayNet. When applied to document-pretrained LayoutLMv3 (133M params), our fusion framework reaches 89.7pm0.4 AP, surpassing both LayoutLMv3 with standard semi-supervised learning (89.1pm0.4 AP, p=0.02) and matching UDOP~udop (89.8 AP) which requires 100M+ pages of multimodal pretraining. This demonstrates that LLM structural priors are complementary to both lightweight and pretrained architectures. Key findings include: (1) learned instance-adaptive gating improves over fixed weights by +0.9 AP with data-dependent PAC bounds correctly predicting convergence; (2) open-source LLMs enable privacy-preserving deployment with minimal loss (Llama-3-70B: 87.1 AP lightweight, 89.4 AP with LayoutLMv3); (3) LLMs provide targeted semantic disambiguation (18.7\% of cases, +3.8 AP gain) beyond simple text heuristics.Total system cost includes \$12 for GPT-4o-mini API or 17 GPU-hours for local Llama-3-70B per 50K pages, amortized across training runs.

  • 3 authors
·
Nov 11, 2025

Skywork-R1V3 Technical Report

We introduce Skywork-R1V3, an advanced, open-source vision-language model (VLM) that pioneers a new approach to visual reasoning. Its key innovation lies in effectively transferring reasoning skills from text-only Large Language Models (LLMs) to visual tasks. The strong performance of Skywork-R1V3 primarily stems from our elaborate post-training RL framework, which effectively activates and enhances the model's reasoning ability, without the need for additional continue pre-training. Through this framework, we further uncover the fundamental role of the connector module in achieving robust cross-modal alignment for multimodal reasoning models. In addition, we introduce a unique indicator of reasoning capability, the entropy of critical reasoning tokens, which has proven highly effective for checkpoint selection during RL training. Skywork-R1V3 achieves state-of-the-art results on MMMU, significantly improving from 64.3% to 76.0%. This performance matches entry-level human capabilities. Remarkably, our RL-powered post-training approach enables even the 38B parameter model to rival top closed-source VLMs. The implementation successfully transfers mathematical reasoning to other subject-related reasoning tasks. We also include an analysis of curriculum learning and reinforcement finetuning strategies, along with a broader discussion on multimodal reasoning. Skywork-R1V3 represents a significant leap in multimodal reasoning, showcasing RL as a powerful engine for advancing open-source VLM capabilities.

Skywork Skywork
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Jul 8, 2025 3

UniEM-3M: A Universal Electron Micrograph Dataset for Microstructural Segmentation and Generation

Quantitative microstructural characterization is fundamental to materials science, where electron micrograph (EM) provides indispensable high-resolution insights. However, progress in deep learning-based EM characterization has been hampered by the scarcity of large-scale, diverse, and expert-annotated datasets, due to acquisition costs, privacy concerns, and annotation complexity. To address this issue, we introduce UniEM-3M, the first large-scale and multimodal EM dataset for instance-level understanding. It comprises 5,091 high-resolution EMs, about 3 million instance segmentation labels, and image-level attribute-disentangled textual descriptions, a subset of which will be made publicly available. Furthermore, we are also releasing a text-to-image diffusion model trained on the entire collection to serve as both a powerful data augmentation tool and a proxy for the complete data distribution. To establish a rigorous benchmark, we evaluate various representative instance segmentation methods on the complete UniEM-3M and present UniEM-Net as a strong baseline model. Quantitative experiments demonstrate that this flow-based model outperforms other advanced methods on this challenging benchmark. Our multifaceted release of a partial dataset, a generative model, and a comprehensive benchmark -- available at huggingface -- will significantly accelerate progress in automated materials analysis.

  • 11 authors
·
Aug 22, 2025

Leveraging Biomolecule and Natural Language through Multi-Modal Learning: A Survey

The integration of biomolecular modeling with natural language (BL) has emerged as a promising interdisciplinary area at the intersection of artificial intelligence, chemistry and biology. This approach leverages the rich, multifaceted descriptions of biomolecules contained within textual data sources to enhance our fundamental understanding and enable downstream computational tasks such as biomolecule property prediction. The fusion of the nuanced narratives expressed through natural language with the structural and functional specifics of biomolecules described via various molecular modeling techniques opens new avenues for comprehensively representing and analyzing biomolecules. By incorporating the contextual language data that surrounds biomolecules into their modeling, BL aims to capture a holistic view encompassing both the symbolic qualities conveyed through language as well as quantitative structural characteristics. In this review, we provide an extensive analysis of recent advancements achieved through cross modeling of biomolecules and natural language. (1) We begin by outlining the technical representations of biomolecules employed, including sequences, 2D graphs, and 3D structures. (2) We then examine in depth the rationale and key objectives underlying effective multi-modal integration of language and molecular data sources. (3) We subsequently survey the practical applications enabled to date in this developing research area. (4) We also compile and summarize the available resources and datasets to facilitate future work. (5) Looking ahead, we identify several promising research directions worthy of further exploration and investment to continue advancing the field. The related resources and contents are updating in https://github.com/QizhiPei/Awesome-Biomolecule-Language-Cross-Modeling.

  • 8 authors
·
Mar 3, 2024

Multi-modal Co-learning for Earth Observation: Enhancing single-modality models via modality collaboration

Multi-modal co-learning is emerging as an effective paradigm in machine learning, enabling models to collaboratively learn from different modalities to enhance single-modality predictions. Earth Observation (EO) represents a quintessential domain for multi-modal data analysis, wherein diverse remote sensors collect data to sense our planet. This unprecedented volume of data introduces novel challenges. Specifically, the access to the same sensor modalities at both training and inference stages becomes increasingly complex based on real-world constraints affecting remote sensing platforms. In this context, multi-modal co-learning presents a promising strategy to leverage the vast amount of sensor-derived data available at the training stage to improve single-modality models for inference-time deployment. Most current research efforts focus on designing customized solutions for either particular downstream tasks or specific modalities available at the inference stage. To address this, we propose a novel multi-modal co-learning framework capable of generalizing across various tasks without targeting a specific modality for inference. Our approach combines contrastive and modality discriminative learning together to guide single-modality models to structure the internal model manifold into modality-shared and modality-specific information. We evaluate our framework on four EO benchmarks spanning classification and regression tasks across different sensor modalities, where only one of the modalities available during training is accessible at inference time. Our results demonstrate consistent predictive improvements over state-of-the-art approaches from the recent machine learning and computer vision literature, as well as EO-specific methods. The obtained findings validate our framework in the single-modality inference scenarios across a diverse range of EO applications.

  • 5 authors
·
Oct 22, 2025 1

MIRROR: Multi-Modal Pathological Self-Supervised Representation Learning via Modality Alignment and Retention

Histopathology and transcriptomics are fundamental modalities in oncology, encapsulating the morphological and molecular aspects of the disease. Multi-modal self-supervised learning has demonstrated remarkable potential in learning pathological representations by integrating diverse data sources. Conventional multi-modal integration methods primarily emphasize modality alignment, while paying insufficient attention to retaining the modality-specific structures. However, unlike conventional scenarios where multi-modal inputs share highly overlapping features, histopathology and transcriptomics exhibit pronounced heterogeneity, offering orthogonal yet complementary insights. Histopathology provides morphological and spatial context, elucidating tissue architecture and cellular topology, whereas transcriptomics delineates molecular signatures through gene expression patterns. This inherent disparity introduces a major challenge in aligning them while maintaining modality-specific fidelity. To address these challenges, we present MIRROR, a novel multi-modal representation learning method designed to foster both modality alignment and retention. MIRROR employs dedicated encoders to extract comprehensive features for each modality, which is further complemented by a modality alignment module to achieve seamless integration between phenotype patterns and molecular profiles. Furthermore, a modality retention module safeguards unique attributes from each modality, while a style clustering module mitigates redundancy and enhances disease-relevant information by modeling and aligning consistent pathological signatures within a clustering space. Extensive evaluations on TCGA cohorts for cancer subtyping and survival analysis highlight MIRROR's superior performance, demonstrating its effectiveness in constructing comprehensive oncological feature representations and benefiting the cancer diagnosis.

  • 7 authors
·
Mar 1, 2025

MiMIC: Multi-Modal Indian Earnings Calls Dataset to Predict Stock Prices

Predicting stock market prices following corporate earnings calls remains a significant challenge for investors and researchers alike, requiring innovative approaches that can process diverse information sources. This study investigates the impact of corporate earnings calls on stock prices by introducing a multi-modal predictive model. We leverage textual data from earnings call transcripts, along with images and tables from accompanying presentations, to forecast stock price movements on the trading day immediately following these calls. To facilitate this research, we developed the MiMIC (Multi-Modal Indian Earnings Calls) dataset, encompassing companies representing the Nifty 50, Nifty MidCap 50, and Nifty Small 50 indices. The dataset includes earnings call transcripts, presentations, fundamentals, technical indicators, and subsequent stock prices. We present a multimodal analytical framework that integrates quantitative variables with predictive signals derived from textual and visual modalities, thereby enabling a holistic approach to feature representation and analysis. This multi-modal approach demonstrates the potential for integrating diverse information sources to enhance financial forecasting accuracy. To promote further research in computational economics, we have made the MiMIC dataset publicly available under the CC-NC-SA-4.0 licence. Our work contributes to the growing body of literature on market reactions to corporate communications and highlights the efficacy of multi-modal machine learning techniques in financial analysis.

  • 3 authors
·
Apr 12, 2025